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Research and review articles are invited for publication in September - October 2026 (Volume 18, Issue 1) Submit manuscript

Revolutionizing Prostate Cancer: Novel therapeutic strategies unveiled

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  • Revolutionizing Prostate Cancer: Novel therapeutic strategies unveiled

Okorochi Chinenye Mary 1, Okorochi, Enoch Chibuike 2, *, Akinyo Adeyinka Samson 3, Jegede Olushola Olakunle 4, Edegbe Felix Osogu 5 and Dike Ejike McNelson Nlemchukwu 6

1 Department of Medical Laboratory Science, Babcock University, Ilishan Remo, Ogun State, Nigeria.
2 Department of Medical Laboratory Science, Joseph Ayo Babalola University, Osun State, Nigeria.
3 Department of Medical Laboratory Science, University of Nigeria, School of Postgraduate Studies, Nsukka, Enugu State. Nigeria. 
4 Department of Anatomical Pathology, Federal Medical Center, Umuahia, Abia State, Nigeria.
5 Department of Anatomic Pathology, Ebonyi State University, Ebonyi State, Nigeria.
6 Department of Radiology, Federal Teaching Hospital, Owerri, Imo State, Nigeria.
Review Article
Magna Scientia Advanced Research and Reviews, 2025, 14(02), 121-133
Article DOI: 10.30574/msarr.2025.14.2.0095
DOI url: https://doi.org/10.30574/msarr.2025.14.2.0095
Received on 27 June 2025; revised on 05 August 2025; accepted on 07 August 2025'
Prostate cancer remains a leading cause of cancer-related morbidity and mortality among men worldwide, necessitating the continuous evolution of therapeutic approaches. This review paper provides a comprehensive analysis of the latest advancements in prostate cancer treatment, highlighting innovative modalities that have the potential to significantly improve clinical outcomes. We systematically explore emerging therapies including targeted molecular agents, immunotherapies, gene editing technologies, and novel drug delivery systems. The review highlights the mechanistic underpinnings and clinical trial data supporting the efficacy and safety of these approaches. Particular attention is given to the integration of precision medicine, which tailors treatment based on genetic and molecular tumor profiling, thereby enhancing therapeutic specificity and minimizing adverse effects. Additionally, we discuss the challenges and limitations associated with current novel therapies, such as resistance development and accessibility issues, alongside potential strategies to overcome these barriers. By synthesizing preclinical and clinical evidence, this paper underscores the paradigm shift from conventional treatments to personalized, mechanism-driven interventions. The review concludes with future perspectives on the role of artificial intelligence and biomarker discovery in optimizing prostate cancer management. Ultimately, this work aims to inform clinicians, researchers, and stakeholders about cutting-edge therapeutic innovations that promise to revolutionize prostate cancer care, thereby improving patient survival and quality of life.
Prostate Cancer; Novel Therapeutic Strategies; Targeted Molecular Agents; Immunotherapy; Precision Medicine; Gene Editing Technologies
https://msarr.magnascientiapub.com/sites/default/files/fulltext_pdf/MSARR-2025-…

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Okorochi Chinenye Mary, Okorochi, Enoch Chibuike, Akinyo Adeyinka Samson, Jegede Olushola Olakunle, Edegbe Felix Osogu and Dike Ejike McNelson Nlemchukwu. Revolutionizing Prostate Cancer: Novel therapeutic strategies unveiled. Magna Scientia Advanced Research and Reviews, 2025, 14(2), 121-133. Article DOI: https://doi.org/10.30574/msarr.2025.14.2.0095

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