The impact of anemia on prolonged ventilator use in critically ill patients: A literature review

Anemia is a common condition associated with critically ill patients admitted to intensive care unit (ICU), where 60% of ICU patients experience anemia and 61% of anemic and tranfused patients present in the ICU require mechanical ventilation. The presence of anemia in critically ill patients is associated with increased risk of mortality, cardiovascular morbidity, and decreased oxygen-carrying capacity, potentially prolonging the need for mechanical ventilation. Mechanical ventilation is the primary method of supporting organ function for patients receiving treatment in the ICU. According to epidemiological studies, up to 70% of patients hospitalized to the ICU require mechanical ventilation at some time during their stay. Studies regarding the correlation between anemia and the length of ventilator use are rarely known. Therefore, researchers are interested in conducting research on the correlation between anemia and length of ventilator use. This review is expected to be useful for enriching knowledge about the relationship between anemia and length of ventilator use in critically ill patients. However, further research is needed with more comprehensive variables to determine the impact of anemia on prolonged ventilator use, risk factors of weaning failure, pathogenesis of anemia, and treatment used in critically ill patients.