Hematological evolution of anti-oxidative effects of Lipidum sativum in albino male rats

The current study aimed to investigate the anti-oxidative effects of Lipidum sativum agonist poisonous mercuric chloride. Total of 60 Swiss male rats were used which allocated into 5 groups; control group (C), mercuric chloride group (M), third, fourth and fifth groups were represented the treatment groups (T1, T2 & T3), each group was divide into two subgroups (21 and 42 days. The blood samples collection by heart puncture for Hematological study. Lepidium sativum extract seed was prepared in doses of 25, 50.100 mg/kg. Results showed in groups that treated with mercury chloride there was decrease in both periods (21 and 42) days in (WBC, RBC, HCT & Hb) and decrease in period of 21 days. In groups that treated with extract of seeds Lipidum sativum (100, 50, 25) mg / kg. showed increased in (WBC & RBC) in both periods. In (Hb) there was increase in the 21-days in (T3).In 42-day showed increase in (T2 & T3). In PVC there was increase in the 21-days. In the 42-day period showed increase all groups. Plate let showed increase at 42 days in treated group in (T1& T2). In MCV showed decrease in groups (T1, T2 & T3) at 21 days. In the 42-days showed a reduction in group (T1). The (MCHC) showed decrease in the 21 days and significant increase in (T2). The result concluded that the Lepidium sativum extract seed has improved the blood parameters against toxic effects of mercuric chloride in short and long term.